DBCO-PEG8-GGFG-DXD

PG-20161-82975

Product information

Catalog No.
PG-20161-82975
Product Name
DBCO-PEG8-GGFG-DXD
CAS No.
Not specified
Molecular Formula
C80H95FN10O21
Molecular Weight
1551.7
Purity
95%
Storage
-20°C
Shipping
Ambient Temperature
Documents

Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.

Packaging & pricing

Packaging and pricing for PG-20161-82975
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General Information

Product Name
DBCO-PEG8-GGFG-DXD
CAS No.
Not specified
Synonyms
Not specified
Molecular Formula
C80H95FN10O21
Molecular Weight
1551.7
Appearance
Not specified
Solubility
Not specified
Description

DBCO-PEG8-GGFG-DXD is a linker-payload construct for antibody–drug conjugate research. A DBCO handle enables copper-free SPAAC conjugation with azide-modified antibodies, while an 8-unit PEG spacer supports aqueous solubility. The construct also incorporates a protease-cleavable GGFG tetrapeptide linker.

The DXD payload is an exatecan derivative that inhibits DNA topoisomerase I. This combination places the compound among cleavable ADC linker-payloads for investigating intracellular payload release. The listed purity is 95%, and storage is specified at -20°C.