3,4-Dibromo-Mal-PEG4-Val-Cit-PAB-MMAE

PG-20161-21632

Product information

Catalog No.
PG-20161-21632
Product Name
3,4-Dibromo-Mal-PEG4-Val-Cit-PAB-MMAE
CAS No.
Not specified
Molecular Formula
C73H113Br2N11O19
Molecular Weight
1608.6
Purity
Not specified
Storage
-20°C
Shipping
Ambient Temperature
Documents

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General Information

Product Name
3,4-Dibromo-Mal-PEG4-Val-Cit-PAB-MMAE
CAS No.
Not specified
Synonyms
Not specified
Molecular Formula
C73H113Br2N11O19
Molecular Weight
1608.6
Appearance
Not specified
Solubility
DMSO, DCM, DMF
Description

3,4-Dibromo-Mal-PEG4-Val-Cit-PAB-MMAE is a peptide linker–payload reagent for constructing antibody drug conjugates (ADCs). Its dibromomaleimide group provides two substitution positions through its two bromine atoms. The Val-Cit-PAB segment incorporates a cathepsin-cleavable peptide linked to an MMAE payload, while the PEG4 chain improves water solubility.

Cataloged among cleavable and site-specific ADC linkers, the compound has molecular formula C73H113Br2N11O19 and molecular weight 1608.6. Listed solvents are DMSO, DCM, DMF, and the specified storage temperature is -20°C.