3,4-Dibromo-Mal-PEG8-Val-Cit-PAB-MMAE
PG-20161-74616
Product information
- Catalog No.
- PG-20161-74616
- Product Name
- 3,4-Dibromo-Mal-PEG8-Val-Cit-PAB-MMAE
- CAS No.
- Not specified
- Molecular Formula
- C81H129Br2N11O23
- Molecular Weight
- 1784.8
- Purity
- 97%
- Storage
- -20°C
- Shipping
- Ambient Temperature
- Documents
Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.
Packaging & pricing
| Catalog No. | Packaging | Price (USD) | Stock | Inquiry action |
|---|---|---|---|---|
| PG-20161-74616 | Please advise | Inquiry | In stock |
Final pricing, package availability and delivery are confirmed with your quotation.
General Information
- Product Name
- 3,4-Dibromo-Mal-PEG8-Val-Cit-PAB-MMAE
- CAS No.
- Not specified
- Synonyms
- Not specified
- Molecular Formula
- C81H129Br2N11O23
- Molecular Weight
- 1784.8
- Appearance
- Not specified
- Solubility
- Not specified
- Description
3,4-Dibromo-Mal-PEG8-Val-Cit-PAB-MMAE is a cleavable linker-payload for antibody-drug conjugate research. Its dibromomaleimide group provides two attachment positions through substitution of the bromine atoms. Intracellular proteases such as Cathepsin B cleave the Val-Cit dipeptide, enabling MMAE release through an elimination mechanism in the PAB unit.
The PEG8 chain contributes to water solubility. This product is listed within the MMAE payload, cleavable linker and site-specific linker categories, with a purity of 97% and a specified storage temperature of -20°C.