Mal-PEG4-Val-Cit-PAB-MMAE

PG-20161-52145

Product information

Catalog No.
PG-20161-52145
Product Name
Mal-PEG4-Val-Cit-PAB-MMAE
CAS No.
Not specified
Molecular Formula
C73H115N11O19
Molecular Weight
1450.8
Purity
98%
Storage
-20°C
Shipping
Ambient Temperature
Documents

Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.

Packaging & pricing

Packaging and pricing for PG-20161-52145
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General Information

Product Name
Mal-PEG4-Val-Cit-PAB-MMAE
CAS No.
Not specified
Synonyms
Not specified
Molecular Formula
C73H115N11O19
Molecular Weight
1450.8
Appearance
Not specified
Solubility
DMSO, DMF
Description

Mal-PEG4-Val-Cit-PAB-MMAE is a cleavable ADC linker incorporating maleimide, a Val-Cit dipeptide, a PAB group and an MMAE payload. The maleimide provides thiol-specific covalent attachment to protein cysteine residues. Protease cleavage of the Val-Cit motif enables intracellular MMAE release through an elimination mechanism.

The product has a molecular formula of C73H115N11O19 and a molecular weight of 1450.8. Its specified purity is 98%, and it is soluble in DMSO and DMF. The listed storage temperature is -20°C.