N3-PEG8-COOH

PG-20161-31833

Product information

Catalog No.
PG-20161-31833
Product Name
N3-PEG8-COOH
CAS No.
1214319-92-2
Molecular Formula
C19H37N3O10
Molecular Weight
467.51
Purity
≥95%
Storage
Store at -5°C,keep in dry and avoid sunlight.
Shipping
Not specified
Documents

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Packaging & pricing

Packaging and pricing for PG-20161-31833
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PG-20161-318331gUSD 150In stock

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General Information

Product Name
N3-PEG8-COOH
CAS No.
1214319-92-2
Synonyms
Azide-PEG8-COOH | Azido-PEG8-acid
Molecular Formula
C19H37N3O10
Molecular Weight
467.51
Appearance
Not specified
Solubility
Not specified
Description

N3-PEG8-COOH is a water-soluble, monodisperse PEG linker containing an azide group and a terminal carboxylic acid group. Its 8-unit PEG segment serves as a non-cleavable linker for antibody–drug conjugate synthesis and as a PEG-based linker for PROTAC synthesis.

The azide reacts with alkynes, including BCN and DBCO, through click chemistry to form a stable triazole linkage. The carboxylic acid supports coupling to primary amines using activators such as EDC or HATU, forming a stable amide bond.