MC-Val-Cit-PAB-Gly-NHS ester
PG-20161-42139
Product information
- Catalog No.
- PG-20161-42139
- Product Name
- MC-Val-Cit-PAB-Gly-NHS ester
- CAS No.
- Not specified
- Molecular Formula
- C35H46N8O12
- Molecular Weight
- 770.8
- Purity
- Not specified
- Storage
- -20°C
- Shipping
- Ambient Temperature
- Documents
Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.
Packaging & pricing
| Catalog No. | Packaging | Price (USD) | Stock | Inquiry action |
|---|---|---|---|---|
| PG-20161-42139 | Please advise | Inquiry | In stock |
Final pricing, package availability and delivery are confirmed with your quotation.
General Information
- Product Name
- MC-Val-Cit-PAB-Gly-NHS ester
- CAS No.
- Not specified
- Synonyms
- Not specified
- Molecular Formula
- C35H46N8O12
- Molecular Weight
- 770.8
- Appearance
- Not specified
- Solubility
- DMSO, DMF
- Description
MC-Val-Cit-PAB-Gly-NHS ester is a cleavable ADC linker containing a maleimide group, a valine-citrulline (Val-Cit) dipeptide and a para-aminobenzyl (PAB) spacer connected to a glycine-NHS residue. The maleimide supports covalent labeling of cysteine thiols in proteins, while the NHS ester reacts with amines.
Protease cleavage of the dipeptide triggers PAB-mediated payload release through an elimination mechanism. Listed under Val-Cit cleavable linkers, the compound has molecular formula C35H46N8O12 and molecular weight 770.8. DMSO and DMF are listed as solubility solvents; the specified storage temperature is -20°C.