Boc-PEG2-Val-Cit-PAB-OH

PG-20161-54522

Product information

Catalog No.
PG-20161-54522
Product Name
Boc-PEG2-Val-Cit-PAB-OH
CAS No.
2055024-55-8
Molecular Formula
C30H50N6O9
Molecular Weight
638.8
Purity
Not specified
Storage
-20°C
Shipping
Ambient Temperature
Documents

Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.

Packaging & pricing

Packaging and pricing for PG-20161-54522
Catalog No.PackagingPrice (USD)StockInquiry action
PG-20161-5452250 MGUSD 181In stock
PG-20161-54522100 MGUSD 307In stock
PG-20161-54522250 MGUSD 522In stock

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General Information

Product Name
Boc-PEG2-Val-Cit-PAB-OH
CAS No.
2055024-55-8
Synonyms
Not specified
Molecular Formula
C30H50N6O9
Molecular Weight
638.8
Appearance
Not specified
Solubility
Not specified
Description

Boc-PEG2-Val-Cit-PAB-OH is an enzyme-cleavable ADC linker with a Boc-protected amine, a hydrophilic PEG spacer and a Val-Cit-PAB segment. Its PAB benzylic alcohol provides a site for activation, including with PNP, for subsequent drug-payload conjugation.

Acid treatment removes the Boc group to expose a primary amine for amide-forming coupling reactions. Cellular proteases cleave the Val-Cit-containing segment to support payload release. The product is cataloged in the Val-Cit cleavable linker range, with a molecular formula of C30H50N6O9.