Fmoc-PEG4-Val-Cit-PAB-OH

PG-20161-84637

Product information

Catalog No.
PG-20161-84637
Product Name
Fmoc-PEG4-Val-Cit-PAB-OH
CAS No.
2055024-58-1
Molecular Formula
C44H60N6O11
Molecular Weight
849
Purity
Not specified
Storage
-20°C
Shipping
Ambient Temperature
Documents

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General Information

Product Name
Fmoc-PEG4-Val-Cit-PAB-OH
CAS No.
2055024-58-1
Synonyms
Not specified
Molecular Formula
C44H60N6O11
Molecular Weight
849
Appearance
Not specified
Solubility
DMSO, DMF
Description

Fmoc-PEG4-Val-Cit-PAB-OH is an enzyme-cleavable linker for antibody-drug conjugate research, incorporating a hydrophilic PEG spacer and a Val-Cit-PAB segment. The PAB benzylic alcohol provides a site for modification to enable drug-payload conjugation. Cellular proteases can cleave the Val-Cit-PAB segment for payload release. Cataloged among Val-Cit cleavable linkers, it has a molecular formula of C44H60N6O11 and a molecular weight of 849. Listed solvents are DMSO and DMF.