TFP-PEG4-Val-Cit-PAB-MMAE

PG-20161-57525

Product information

Catalog No.
PG-20161-57525
Product Name
TFP-PEG4-Val-Cit-PAB-MMAE
CAS No.
Not specified
Molecular Formula
C76H114F4N10O19
Molecular Weight
1547.8
Purity
98%
Storage
-20°C
Shipping
Ambient Temperature
Documents

Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.

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General Information

Product Name
TFP-PEG4-Val-Cit-PAB-MMAE
CAS No.
Not specified
Synonyms
Not specified
Molecular Formula
C76H114F4N10O19
Molecular Weight
1547.8
Appearance
Not specified
Solubility
DMSO, DMF
Description

TFP-PEG4-Val-Cit-PAB-MMAE is a linker-payload precursor for antibody–drug conjugate research. It combines an amine-reactive TFP ester with a cathepsin-cleavable Val-Cit peptide, a PAB spacer and an MMAE payload. The TFP ester is less susceptible to hydrolysis than an NHS ester and supports attachment to a monoclonal antibody.

This cleavable ADC linker-payload has molecular formula C76H114F4N10O19, molecular weight 1547.8 and purity 98%. It is soluble in DMSO and DMF; the specified storage temperature is -20°C.