Lipid I97 (10mg/ml solution in methyl acetate)

PG-20161-66002

Product information

Catalog No.
PG-20161-66002
Product Name
Lipid I97 (10mg/ml solution in methyl acetate)
CAS No.
3046404-81-0
Molecular Formula
C55H102N2O11
Molecular Weight
967.4
Purity
Not specified
Storage
-20°C
Shipping
Ambient Temperature
Documents

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General Information

Product Name
Lipid I97 (10mg/ml solution in methyl acetate)
CAS No.
3046404-81-0
Synonyms
Not specified
Molecular Formula
C55H102N2O11
Molecular Weight
967.4
Appearance
Not specified
Solubility
Not specified
Description

Lipid I97 (10mg/ml solution in methyl acetate) contains a vitamin B5-derived ionizable cationic lipid with pKa = 6.23. Lipid I97 has been used to prepare lipid nanoparticles (LNPs) for in vivo mRNA delivery and is cataloged within the Ionizable Lipid collection.

In mouse studies, LNPs containing lipid I97 and luciferase mRNA selectively accumulated in the spleen and lymph nodes. Formulations encapsulating mRNA encoding hemagglutinin A induced IgG1 and IgG2 production in mice.