Mal-PEG4-Val-Cit-PAB-MMAF

PG-20161-68201

Product information

Catalog No.
PG-20161-68201
Product Name
Mal-PEG4-Val-Cit-PAB-MMAF
CAS No.
Not specified
Molecular Formula
C73H113N11O20
Molecular Weight
1464.8
Purity
95%
Storage
-20°C
Shipping
Ambient Temperature
Documents

Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.

Packaging & pricing

Packaging and pricing for PG-20161-68201
Catalog No.PackagingPrice (USD)StockInquiry action
PG-20161-682015 MGInquiryIn stock
PG-20161-6820110 MGInquiryIn stock
PG-20161-6820125 MGInquiryIn stock

Final pricing, package availability and delivery are confirmed with your quotation.

Your inquiry

Choose a package above to start your inquiry.

View inquiry (0)

General Information

Product Name
Mal-PEG4-Val-Cit-PAB-MMAF
CAS No.
Not specified
Synonyms
Not specified
Molecular Formula
C73H113N11O20
Molecular Weight
1464.8
Appearance
Not specified
Solubility
DMSO, DMF
Description

Mal-PEG4-Val-Cit-PAB-MMAF is an ADC linker-payload construct combining a thiol-specific maleimide with an enzymatically cleavable Val-Cit site and the MMAF payload. The maleimide labels cysteine residues in proteins, while the Val-Cit segment provides a site for Cathepsin B cleavage. MMAF is a synthetic antineoplastic agent used as a cytotoxic payload. The PEG chain enhances aqueous solubility; listed solvents are DMSO, DMF.