E12CA1A3 (solution in ethanol)

PG-20161-81055

Product information

Catalog No.
PG-20161-81055
Product Name
E12CA1A3 (solution in ethanol)
CAS No.
2778182-26-4
Molecular Formula
C34H67NO4
Molecular Weight
553.9
Purity
Not specified
Storage
-20°C
Shipping
Ambient Temperature
Documents

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General Information

Product Name
E12CA1A3 (solution in ethanol)
CAS No.
2778182-26-4
Synonyms
Not specified
Molecular Formula
C34H67NO4
Molecular Weight
553.9
Appearance
Not specified
Solubility
Not specified
Description

E12CA1A3 (solution in ethanol) contains an ionizable cationic lipid with pKa = 6.4, used in lipid nanoparticle (LNP) formulations for mRNA delivery in vitro and in vivo. Reporter mRNA formulations have produced luciferase expression in mouse bone marrow-derived dendritic cells (BMDCs) and live mice. In mice, E12CA1A3-based LNPs have also shown faster liver clearance than DLin-MC3-DMA-based LNPs.