TCO-PEG4-Val-Cit-PAB-PNP

PG-20161-82895

Product information

Catalog No.
PG-20161-82895
Product Name
TCO-PEG4-Val-Cit-PAB-PNP
CAS No.
Not specified
Molecular Formula
C45H65N7O15
Molecular Weight
944.1
Purity
98%
Storage
-20°C
Shipping
Ambient Temperature
Documents

Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.

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General Information

Product Name
TCO-PEG4-Val-Cit-PAB-PNP
CAS No.
Not specified
Synonyms
Not specified
Molecular Formula
C45H65N7O15
Molecular Weight
944.1
Appearance
Not specified
Solubility
DMSO, DMF
Description

TCO-PEG4-Val-Cit-PAB-PNP is a cleavable peptide linker for ADC linker and click chemistry research. Its Val-Cit segment is cleaved by Cathepsin B, while PNP serves as a leaving group in nucleophilic reactions. The TCO group reacts with tetrazines through inverse-electron demand Diels-Alder cycloaddition.

The product has a molecular formula of C45H65N7O15, a molecular weight of 944.1 and a stated purity of 98%. It is soluble in DMSO, DMF, with a listed storage temperature of -20°C. TCO can isomerize to the unreactive cis form, so long-term storage is not recommended.