Azido-PEG12-Amido-Val-Cit-PAB-PNP

PG-20161-33604

Product information

Catalog No.
PG-20161-33604
Product Name
Azido-PEG12-Amido-Val-Cit-PAB-PNP
CAS No.
Not specified
Molecular Formula
C55H88N10O23
Molecular Weight
1257.4
Purity
98%
Storage
-20°C
Shipping
Ambient Temperature
Documents

Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.

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General Information

Product Name
Azido-PEG12-Amido-Val-Cit-PAB-PNP
CAS No.
Not specified
Synonyms
Not specified
Molecular Formula
C55H88N10O23
Molecular Weight
1257.4
Appearance
Not specified
Solubility
Not specified
Description

Azido-PEG12-Amido-Val-Cit-PAB-PNP is a cleavable, azide-functionalized linker for antibody-drug conjugate research. Its azido group supports click chemistry with alkynes, BCN and DBCO, while the Val-Cit segment is designed for cleavage by cathepsin B. The PNP group serves as a leaving group in reactions with amine-bearing payloads.

The PEG12 segment enhances water solubility. This combination of click-reactive functionality, a cleavable peptide segment and a payload-coupling group supports its use in ADC linker assembly.