Mal-amido-PEG8-val-gly-PAB-OH
PG-20161-34192
Product information
- Catalog No.
- PG-20161-34192
- Product Name
- Mal-amido-PEG8-val-gly-PAB-OH
- CAS No.
- 2353409-52-4
- Molecular Formula
- C40H63N5O15
- Molecular Weight
- 854
- Purity
- 98%
- Storage
- -20°C
- Shipping
- Ambient Temperature
- Documents
Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.
Packaging & pricing
| Catalog No. | Packaging | Price (USD) | Stock | Inquiry action |
|---|---|---|---|---|
| PG-20161-34192 | 5 MG | USD 1,601 | In stock | |
| PG-20161-34192 | 10 MG | USD 3,066 | In stock | |
| PG-20161-34192 | 50 MG | USD 14,136 | In stock |
Prices are shown in USD. Final pricing, package availability and delivery are confirmed with your quotation.
General Information
- Product Name
- Mal-amido-PEG8-val-gly-PAB-OH
- CAS No.
- 2353409-52-4
- Synonyms
- Not specified
- Molecular Formula
- C40H63N5O15
- Molecular Weight
- 854
- Appearance
- Not specified
- Solubility
- Not specified
- Description
Mal-amido-PEG8-val-gly-PAB-OH is a cleavable ADC linker combining a maleimide group, a hydrophilic PEG spacer, a Val-Gly dipeptide and a PAB group bearing a free benzylic alcohol. The maleimide enables covalent coupling to free cysteine thiols on proteins, while the benzylic alcohol provides a site for derivatization with reactive groups such as PNP for subsequent payload conjugation.
Intracellular protease cleavage of the Val-Gly sequence enables payload release through an elimination mechanism involving the PAB group. The listed molecular formula is C40H63N5O15, with a molecular weight of 854 and purity of 98%.