PPPDA-O16B (solution in methyl acetate)
PG-20161-78240
Product information
- Catalog No.
- PG-20161-78240
- Product Name
- PPPDA-O16B (solution in methyl acetate)
- CAS No.
- Not specified
- Molecular Formula
- C37H73NO4S4
- Molecular Weight
- 724.3
- Purity
- Not specified
- Storage
- -20°C
- Shipping
- Ambient Temperature
- Documents
Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.
Packaging & pricing
| Catalog No. | Packaging | Price (USD) | Stock | Inquiry action |
|---|---|---|---|---|
| PG-20161-78240 | 5 MG | Inquiry | In stock | |
| PG-20161-78240 | 10 MG | Inquiry | In stock | |
| PG-20161-78240 | 25 MG | Inquiry | In stock |
Final pricing, package availability and delivery are confirmed with your quotation.
General Information
- Product Name
- PPPDA-O16B (solution in methyl acetate)
- CAS No.
- Not specified
- Synonyms
- Not specified
- Molecular Formula
- C37H73NO4S4
- Molecular Weight
- 724.3
- Appearance
- Not specified
- Solubility
- Not specified
- Description
PPPDA-O16B (solution in methyl acetate) contains a disulfide-bearing ionizable cationic lipid used in lipid nanoparticles (LNPs) for plasmid delivery in vitro and in vivo. It is cataloged within the ionizable lipid and multi chargeable lipid categories.
In reported research, LNPs carrying plasmids encoding Ras/Rap1-specific endopeptidase (RRSP) increased RRSP expression, reduced Ras levels, and decreased HeLa cervical cancer cell viability. In an HCT116 colorectal cancer mouse xenograft model, these formulations preferentially accumulated in tumors over the examined organs and reduced tumor volume without observed weight loss.