BI 9564

PG-20161-80773

Product information

Catalog No.
PG-20161-80773
Product Name
BI 9564
CAS No.
1883429-22-8
Molecular Formula
C20H23N3O3
Molecular Weight
353.4
Purity
Not specified
Storage
-20°C
Shipping
Ambient Temperature
Documents

Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.

Packaging & pricing

Packaging and pricing for PG-20161-80773
Catalog No.PackagingPrice (USD)StockInquiry action
PG-20161-8077310 MGUSD 103In stock
PG-20161-8077325 MGUSD 196In stock
PG-20161-8077350 MGUSD 332In stock

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General Information

Product Name
BI 9564
CAS No.
1883429-22-8
Synonyms
Not specified
Molecular Formula
C20H23N3O3
Molecular Weight
353.4
Appearance
Not specified
Solubility
Not specified
Description

BI 9564 is a selective inhibitor of the BRD9 and BRD7 bromodomains, with Kds of 14.1 and 239 nM, respectively. Cellular activity measured by semi-quantitative FRAP assay showed ~90% inhibition of BRD9 at 0.1 µM and BRD7 at 1 µM.

In preclinical research, BI 9564 inhibits proliferation of AML cell lines in vitro and reduces AML tumor xenograft growth in vivo. It is cataloged within the inhibitor section of the PROTAC Linkers collection.