Fmoc-PEG4-Val-Cit-PAB-PNP

PG-20161-29465

Product information

Catalog No.
PG-20161-29465
Product Name
Fmoc-PEG4-Val-Cit-PAB-PNP
CAS No.
Not specified
Molecular Formula
C51H63N7O15
Molecular Weight
1014.1
Purity
98%
Storage
-20°C
Shipping
Ambient Temperature
Documents

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General Information

Product Name
Fmoc-PEG4-Val-Cit-PAB-PNP
CAS No.
Not specified
Synonyms
Not specified
Molecular Formula
C51H63N7O15
Molecular Weight
1014.1
Appearance
Not specified
Solubility
DMSO, DMF
Description

Fmoc-PEG4-Val-Cit-PAB-PNP is a cleavable ADC linker containing a Cathepsin B-sensitive Val-Cit dipeptide for lysosomal payload release. It includes an Fmoc protecting group removable under basic conditions and an amine-reactive PNP group that serves as a leaving group. The compound has molecular formula C51H63N7O15, molecular weight 1014.1 and purity 98%. It is soluble in DMSO and DMF.