NI 57
PG-20161-33909
Product information
- Catalog No.
- PG-20161-33909
- Product Name
- NI 57
- CAS No.
- 1883548-89-7
- Molecular Formula
- C19H17N3O4S
- Molecular Weight
- 383.4
- Purity
- Not specified
- Storage
- -20°C
- Shipping
- Ambient Temperature
- Documents
Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.
Packaging & pricing
| Catalog No. | Packaging | Price (USD) | Stock | Inquiry action |
|---|---|---|---|---|
| PG-20161-33909 | 10 MG | USD 117 | In stock | |
| PG-20161-33909 | 25 MG | USD 233 | In stock |
Prices are shown in USD. Final pricing, package availability and delivery are confirmed with your quotation.
General Information
- Product Name
- NI 57
- CAS No.
- 1883548-89-7
- Synonyms
- Not specified
- Molecular Formula
- C19H17N3O4S
- Molecular Weight
- 383.4
- Appearance
- Not specified
- Solubility
- Not specified
- Description
NI 57 is an inhibitor of the BRPF (Bromodomain and PHD Finger) protein family, encompassing BRPF1/2/3. Reported Kd values are 31, 108 and 408 nM for BRPF1B, 2 and 3, respectively, with >32-fold selectivity for BRPFs over BRD9 and other non-Class IV bromodomains.
NI 57 inhibits RANKL-induced osteoclast differentiation in primary murine bone marrow cells and human primary monocytes. It is listed in the BRPF inhibitor category within PROTAC Linkers. Its molecular formula is C19H17N3O4S, and its molecular weight is 383.4.