N-piperidine Ibrutinib hydrochloride

PG-20161-85961

Product information

Catalog No.
PG-20161-85961
Product Name
N-piperidine Ibrutinib hydrochloride
CAS No.
2231747-18-3
Molecular Formula
C22H22N6O
Molecular Weight
386.5
Purity
Not specified
Storage
-20°C
Shipping
Ambient Temperature
Documents

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Packaging & pricing

Packaging and pricing for PG-20161-85961
Catalog No.PackagingPrice (USD)StockInquiry action
PG-20161-8596110 MGUSD 114In stock
PG-20161-8596125 MGUSD 217In stock
PG-20161-8596150 MGUSD 369In stock
PG-20161-85961100 MGUSD 628In stock

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General Information

Product Name
N-piperidine Ibrutinib hydrochloride
CAS No.
2231747-18-3
Synonyms
Not specified
Molecular Formula
C22H22N6O
Molecular Weight
386.5
Appearance
Not specified
Solubility
Not specified
Description

N-piperidine Ibrutinib hydrochloride is a reversible ibrutinib derivative used as a BTK inhibitor and as a BTK-binding ligand for PROTAC synthesis. Reported IC50s are 51.0 and 30.7 nM for WT BTK and C481S BTK, respectively. Its research applications include incorporation into BTK-targeting PROTACs such as SJF620, aligning with its placement in the BTK inhibitor section of the PROTAC catalog.