NH2-PEG1-Val-Cit-PAB-OH
PG-20161-91425
Product information
- Catalog No.
- PG-20161-91425
- Product Name
- NH2-PEG1-Val-Cit-PAB-OH
- CAS No.
- 2055024-63-8
- Molecular Formula
- C23H38N6O6
- Molecular Weight
- 494.6
- Purity
- Not specified
- Storage
- -20°C
- Shipping
- Ambient Temperature
- Documents
Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.
Packaging & pricing
| Catalog No. | Packaging | Price (USD) | Stock | Inquiry action |
|---|---|---|---|---|
| PG-20161-91425 | 50 MG | Inquiry | In stock | |
| PG-20161-91425 | 100 MG | Inquiry | In stock | |
| PG-20161-91425 | 250 MG | Inquiry | In stock | |
| PG-20161-91425 | 500 MG | Inquiry | In stock |
Final pricing, package availability and delivery are confirmed with your quotation.
General Information
- Product Name
- NH2-PEG1-Val-Cit-PAB-OH
- CAS No.
- 2055024-63-8
- Synonyms
- Not specified
- Molecular Formula
- C23H38N6O6
- Molecular Weight
- 494.6
- Appearance
- Not specified
- Solubility
- Not specified
- Description
NH2-PEG1-Val-Cit-PAB-OH is a cleavable ADC linker intermediate combining a primary amine, a hydrophilic PEG spacer, a Val-Cit dipeptide and a PAB group bearing a benzylic alcohol. The amine supports coupling with carboxylic acids and reductive amination with aldehydes or ketones, while the alcohol provides a site for activation and subsequent drug-payload conjugation.
Intracellular protease cleavage of the Val-Cit segment enables payload release through an elimination mechanism in the PAB unit. This architecture supports its use in constructing protease-cleavable antibody–drug conjugate linkers.