NH2-PEG6-Val-Cit-PAB-OH

PG-20161-48551

Product information

Catalog No.
PG-20161-48551
Product Name
NH2-PEG6-Val-Cit-PAB-OH
CAS No.
2055024-60-5
Molecular Formula
C33H58N6O11
Molecular Weight
714.9
Purity
Not specified
Storage
-20°C
Shipping
Ambient Temperature
Documents

Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.

Packaging & pricing

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General Information

Product Name
NH2-PEG6-Val-Cit-PAB-OH
CAS No.
2055024-60-5
Synonyms
Not specified
Molecular Formula
C33H58N6O11
Molecular Weight
714.9
Appearance
Not specified
Solubility
Water, DMSO, DMF
Description

NH2-PEG6-Val-Cit-PAB-OH is a cleavable ADC linker combining a primary amine, a hydrophilic PEG spacer, a Val-Cit dipeptide and a PAB group bearing a benzylic alcohol. The amine provides a site for reactions including carboxylic acid coupling and reductive amination, while the benzylic alcohol supports functionalization for payload conjugation.

Cellular protease cleavage of the Val-Cit segment initiates an elimination process within the PAB structure to release the attached payload. The compound is soluble in Water, DMSO, DMF and has a molecular formula of C33H58N6O11.