TCO-PEG2-acid

PG-20161-32725

Product information

Catalog No.
PG-20161-32725
Product Name
TCO-PEG2-acid
CAS No.
2250217-31-1
Molecular Formula
C16H27NO6
Molecular Weight
329.4
Purity
95%
Storage
-20°C
Shipping
Ambient Temperature
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General Information

Product Name
TCO-PEG2-acid
CAS No.
2250217-31-1
Synonyms
Not specified
Molecular Formula
C16H27NO6
Molecular Weight
329.4
Appearance
Not specified
Solubility
DMSO. DCM, DMF
Description

TCO-PEG2-acid is a PEG-based click chemistry linker bearing a TCO group and a terminal carboxylic acid. With an activator such as EDC, the acid group can react with primary amines. The TCO group reacts readily with tetrazines through an inverse electron demand Diels Alder (IEDDA) reaction followed by a retro-DA step. The hydrophilic PEG spacer increases solubility in aqueous media.

TCO can isomerize to the cis form, CCO, with loss of reactivity, so long-term storage is not recommended. The specified storage temperature is -20°C; listed purity is 95%.