TCO-PEG12-acid

PG-20161-52670

Product information

Catalog No.
PG-20161-52670
Product Name
TCO-PEG12-acid
CAS No.
Not specified
Molecular Formula
C36H67NO16
Molecular Weight
769.9
Purity
98%
Storage
-20°C
Shipping
Ambient Temperature
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General Information

Product Name
TCO-PEG12-acid
CAS No.
Not specified
Synonyms
Not specified
Molecular Formula
C36H67NO16
Molecular Weight
769.9
Appearance
Not specified
Solubility
Water, DMSO, DCM, DMF
Description

TCO-PEG12-acid is a PEG linker bearing a TCO moiety and a terminal carboxylic acid. The acid group supports coupling to primary amines in the presence of EDC, while the TCO group reacts with tetrazine-containing molecules through an inverse-electron-demand Diels–Alder cycloaddition to form a stable covalent bond.

The linker is soluble in Water, DMSO, DCM, DMF. Storage is specified at -20°C, but prolonged storage is not recommended because TCO can isomerize to its cis form and lose reactivity toward tetrazines.